MD Anderson Cancer Center Molecular and Cellular Characterization Laboratory (Pancreatic)

Dr. Maitra and team seek to develop a framework that integrates quantitative assessment of diagnostic imaging data with the host immune responses and systemic (circulating) biomarkers elicited by an underlying pancreatic cystic neoplasm, in order to generate algorithms that can reliably distinguish between indolent and aggressive lesions. Understanding the interactions between biology and physics of cystic lesions of the pancreas, where the genetic drivers of pancreatic cyst formation interact with the physical microenvironment to fuel malignant progression reflected in measurable imaging features and humoral immune responses, will offer transformative scientific and clinical approaches to pancreatic cancer and its early detection.