University of Vermont Molecular Characterization Laboratory (Breast)

Dr. Stein and team will leverage existing national and Vermont statewide registries of integrated clinical, radiology, pathology, treatment and outcomes data with matching biospecimens from breast cancer patients to identify molecular and cellular signatures in tumor microenvironment that are predictive of aggressiveness of early stage screen-detected breast cancers. Their approach is to characterize the cell composition and cell-specific gene expression patterns with focus on tumor microenvironments of aggressive interval- and symptom-detected breast cancers.